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How is this different from irritable bowel syndrome (IBS)?

Many patients that are diagnosed with irritable bowel syndrome actually have the Habba Syndrome.

Patients with the Habba Syndrome do not usually get better with standard IBS therapy such as a high fiber diet, antispasmodics or antidiarrheal agents. In fact, many IBS patients that get post-prandial diarrhea (diarrhea after eating) turn out to have the Habba Syndrome and have failed the standard therapy for IBS including the use of antidepressants and antianxiety drugs.


Characteristics of Irritable Bowel Syndrome versus Habba Syndrome

Irritable Bowel Syndrome Habba Syndrome
Associated with abdominal pain/cramps No abdominal pain
Altered bowel habits
(constipation/diarrhea)
Always post-prandial diarrhea
No change with fasting Improves with fasting
Normal gallbladder function Poor gallbladder function
Good response to antispasmodics Poor response to antispasmodics
Unpredictable response to bile acid resins Excellent response to bile acid resins


Am. J. Gastroenterol 2001. 96:600